usual interstitial pneumonia


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usual interstitial pneumonia

Pulmonology A condition of middle-aged individuals, often associated with connective tissue disease, characterized by insidious deterioration of respiratory function with dyspnea, tachypnea, right-sided heart failure, ↓ lung capacity, ↓ residual volume Imaging Early, 'ground-glass', linear or nodular markings, followed by coarsened shadows and cyst formation; diaphragmatic elevation in end-stage UIP reflects tissue loss Management None effective, possibly corticosteroids
References in periodicals archive ?
Using 135 samples obtained through less-invasive transbronchial biopsy (TBB), Veracyte researchers demonstrated the classifier's ability to accurately distinguish the presence of usual interstitial pneumonia (UIP), a pathology pattern whose presence is essential to IPF diagnosis, from samples without UIP (area under curve of 93 percent).
The histopathology of ILD in PM-DM have shown several patterns, including bronchiolitis obliterans with organizing pneumonia, diffuse alveolar damage (DAD), nonspecific interstitial pneumonia (NSIP), and usual interstitial pneumonia (UIP).
For those with subacute or chronic presentations, one should consider interstitial lung disease with a usual interstitial pneumonia or nonspecific interstitial pneumonia pattern, PAP, organizing pneumonia, chronic eosinophilic pneumonia, and malignancy (1).
Identification of a characteristic usual interstitial pneumonia (UIP) or NSIP pattern on high-resolution computerised tomography (HRCT) scan is the initial step in making a definitive diagnosis of IPF and iNSIP, respectively (Table 3).
The definitive diagnosis--by high-resolution computed tomography (HRCT) and/or surgical lung biopsy--depends on the finding of what is referred to as a usual interstitial pneumonia (UIP) pattern, (1), (4) as distinct from an NSIP pattern.
Diffuse alveolar damage and usual interstitial pneumonia are poor prognostic subtypes, with only a 33% 5-years survival rate (13).
Organization of inflammatory exudates leads to intra-alveolar fibrosis, a process reversible by corticosteroids, in contrast to the usual interstitial pneumonia (1).
Both IPF and CFA are associated with the histopathological pattern of usual interstitial pneumonia (UIP).
High-resolution computed tomography features of nonspecific interstitial pneumonia and usual interstitial pneumonia.
Conditions which are associated with interstitial fibrosis at the lung bases, such as asbestosis, usual interstitial pneumonia, scleroderma and rheumatoid lung, are commonly associated with a decrease in lung volume on the chest radiograph over time.
A histologic pattern of nonspecific interstitial pneumonia is associated with a better prognosis than usual interstitial pneumonia in patients with cryptogenic fibrosing alveolitis.
Initially, we considered usual interstitial pneumonia, but we determined that the clinical findings are most consistent with HP.