Ursodeoxycholate | definition of ursodeoxycholate by Medical dictionary
a hydrophilic bile acid, used in the treatment of chronic hepatic disease.
References in periodicals archive
By contrast, the hydrophilic (water soluble) bile acid, ursodeoxycholate
("Ursodiol") negates the tumor-promoting effects of cholic acid in the AOM rat model induced colon cancer and has undergone clinical trials for the prevention of neoplasia in patients at risk for colon cancer.
Heuman DM, Bajaj R: Ursodeoxycholate
conjugates protects against disruption of cholesterol-rich membranes by bile salts.
Bile salt-induced cytotoxicity and ursodeoxycholate
cytoprotection: in-vitro study in perifused rat hepatocytes.