urobilinogen /uro·bi·lino·gen/ (-bi-lin´o-jen) a colorless compound formed in the intestines by reduction of bilirubin.
urobilinogen
urobilinogen [u″ro-bi-lin´o-jen]
u·ro·bi·lin·o·gen (y r  -b -l n  -jn, -j n)n. The precursor of urobilin and a product of the reduction of bilirubin. |
urobilinogen
[yoo͡r′əbīlin′əjən]
a colorless compound formed in the intestine after the breakdown of bilirubin by bacteria. Some of this substance is excreted in feces, and some is resorbed and excreted again in bile or urine. See also urobilin.
urobilinogen [u″ro-bi-lin´o-jen]
a colorless compound formed in the intestines by the reduction of bilirubin; the urobilinogen in the urine normally represents about 1 per cent of the bilirubin produced in the body by the breakdown of hemoglobin. Increased amounts in the urine indicate excessive bilirubin in the blood. Determination of the amount of urobilinogen excreted in a given period makes it possible to evaluate certain types of hemolytic anemia and also is of help in diagnosing liver dysfunction.
Laboratory tests for urobilinogen require collection of urine for a 24-hour period or for a 2-hour period. The 2-hour afternoon collection of urine is most commonly used because it is more convenient and also because it has been found that the excretion of urobilinogen reaches its maximum in the period from midafternoon to late evening. There is no special preparation of the patient for these tests. The exact time period in which the urine has been collected must be noted. The specimen should be taken to the laboratory immediately, since bacteria that may be present in the urine can oxidize urobilinogen and change it to urobilin.
Laboratory tests for urobilinogen require collection of urine for a 24-hour period or for a 2-hour period. The 2-hour afternoon collection of urine is most commonly used because it is more convenient and also because it has been found that the excretion of urobilinogen reaches its maximum in the period from midafternoon to late evening. There is no special preparation of the patient for these tests. The exact time period in which the urine has been collected must be noted. The specimen should be taken to the laboratory immediately, since bacteria that may be present in the urine can oxidize urobilinogen and change it to urobilin.
urobilinogen
a colorless compound formed in the intestines by the reduction of bilirubin. Small amounts of the bilirubin produced in the body by the breakdown of hemoglobin are excreted in the urine as urobilinogen. Increased amounts of urobilinogen in the urine indicate an excessive amount of bilirubin in the blood. Determination of the amount of urobilinogen excreted in a given period makes it possible to evaluate certain types of hemolytic anemia and also is of help in diagnosing liver dysfunction such as hepatocellular damage.
fecal urobilinogen
a group of urobilinoid substances which react with Ehrlich's reagent. Presence indicates an open bile duct and a functional enterohepatic circulation of bile pigments.
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