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Creatinine |
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creatinine /cre·at·i·nine/ (kre-at´i-nin) an anhydride of creatine, the end product of phosphocreatine metabolism; measurements of its rate of urinary excretion are used as diagnostic indicators of kidney function and muscle mass.
Creatinine The metabolized by-product of creatine, an organic acid that assists the body in producing muscle contractions. Creatinine is found in the bloodstream and in muscle tissue. It is removed from the blood by the kidneys and excreted in the urine. Mentioned in: Acute Kidney Failure, Enlarged Prostate, Goodpasture's Syndrome, Kidney Function Tests creatinine (krēat´ n a substance formed from the metabolism of creatine, commonly found in blood, urine, and muscle tissue. creatinine a nitrogenous compound formed as the irreversible end product of creatine metabolism. It is formed in the muscle in relatively small amounts, passes into the blood and is excreted in the urine. A laboratory test for the creatinine level in the blood may be used as a measurement of kidney function. Since creatinine is normally produced in fairly constant amounts as a result of the breakdown of phosphocreatine and is excreted in the urine, an elevation in the creatinine level in the blood indicates a disturbance in kidney function. creatinine:blood urea nitrogen ratio determination of blood creatinine and blood urea nitrogen (BUN) and the relationship between them is an additional assessment of renal function. It may be useful in the differential diagnosis of azotemia and in monitoring renal disease when protein-restricted diets are being given. creatinine clearance test a measure of renal function based on the rate at which ingested creatinine is filtered through the renal glomeruli. creatinine:cortisol ratio see cortisol:creatinine ratio. creatinine-protein ratio protein-creatinine ratio. urine creatinine/serum creatinine ratio used to distinguish between prerenal and renal azotemia. |
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