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uric acid

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
uric acid /uric ac·id/ (u´rik) the water-insoluble end product of primate purine metabolism; deposition of it as crystals in the joints and kidneys causes gout.
uric acid
n.
A semisolid compound that is a nitrogenous end product of protein and purine metabolism and is a nitrogenous component of urine.

Uric acid
A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts.
Mentioned in: Uric Acid Tests

uric acid
[yoo͡r′ik]
a product of the metabolism of protein that is present in the blood and excreted in the urine. Normal adult levels of blood uric acid range from 2.0 to 8.5 mg/dL, with slightly higher values for elderly patients. See also gout, kidney, liver, purine, urine.

uric [u´rik]
uric acid the end product of purine metabolism or oxidation in the body. It is present in blood in a concentration of about 5 mg/100 ml and is excreted in the urine in amounts of a little less than 1 g per day. In gout there is an excess of uric acid in the blood, and its salts, the urates, form insoluble stones in the urinary tract, or may crystallize and form deposits (see tophus) in the joints and tissues. The presence of high concentrations of uric acid in the urine is significant in the diagnosis of gout, but is of little significance in urinary disorders.

uric acid (yoor´ik),
n a product of protein metabolism and present in the blood and urine. See also gout.

uric
pertaining to the urine.

uric acid
the end product of purine metabolism or oxidation in the body in species other than dogs which metabolize uric acid to allantoin (except Dalmatians). Amounts of more than 1 mg/100 ml of uric acid in the blood are an indication of hepatic insufficiency. In birds excess amounts of uric acid and urates in tissue occur in visceral gout.
uric acid calculi
see urate urolith.

uric acid
A small purine metabolite excreted primarily by the kidneys, less by the GI tract; ↑ UA occurs in gout, which primarly affects acral joints, associated with deposition of UA crystals in various tissues; ↑ UA occurs in rapid cell turnover–eg, cancer–leukemia, metastases, myeloma, as well as in alcoholism, dehydration due to diuretics, DM, hyperlipoproteinemia, lead poisoning, renal failure, rarely, idiopathic Ref range Serum, ♂, 3.6-8.3 mg/dL; ♀, 2.2-6.8 mg/dL. See Gout. Cf Synovial fluid analysis.


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There have been several studies showing that higher vitamin C intake significantly reduces serum uric acid levels, yet the relation with risk of gout is unknown and no study has provided evidence of an inverse association between vitamin C intake and risk of gout.
The reason for this is if the kidneys are not functioning at their best, they struggle to process and remove excess uric acid from the body, allowing it to build up in the bloodstream and ultimately crystallize in the joints.
Gout is caused by the kidney producing too much uric acid, and water dilutes the acid and prevents it from settling in the joints in crystal form.
 
 
 
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