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uric acid |
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uric acid /uric ac·id/ (u´rik) the water-insoluble end product of primate purine metabolism; deposition of it as crystals in the joints and kidneys causes gout.
Uric acid A compound resulting from the body's breakdown of purine. It is normally present in human urine only in small amounts. Mentioned in: Uric Acid Tests
uric acid [yoo͡r′ik] uric [u´rik] uric acid the end product of purine metabolism or oxidation in the body. It is present in blood in a concentration of about 5 mg/100 ml and is excreted in the urine in amounts of a little less than 1 g per day. In gout there is an excess of uric acid in the blood, and its salts, the urates, form insoluble stones in the urinary tract, or may crystallize and form deposits (see tophus) in the joints and tissues. The presence of high concentrations of uric acid in the urine is significant in the diagnosis of gout, but is of little significance in urinary disorders.
uric acid (yoor´ik), n a product of protein metabolism and present in the blood and urine. See also gout.
uric pertaining to the urine. uric acid the end product of purine metabolism or oxidation in the body in species other than dogs which metabolize uric acid to allantoin (except Dalmatians). Amounts of more than 1 mg/100 ml of uric acid in the blood are an indication of hepatic insufficiency. In birds excess amounts of uric acid and urates in tissue occur in visceral gout. uric acid calculi
see urate urolith. uric acid A small purine metabolite excreted primarily by the kidneys, less by the GI tract; ↑ UA occurs in gout, which primarly affects acral joints, associated with deposition of UA crystals in various tissues; ↑ UA occurs in
rapid cell turnover–eg, cancer–leukemia, metastases, myeloma, as well as in alcoholism, dehydration due to diuretics, DM, hyperlipoproteinemia, lead poisoning, renal failure, rarely, idiopathic Ref range Serum, ♂, 3.6-8.3 mg/dL;
♀, 2.2-6.8 mg/dL. See Gout. Cf Synovial fluid analysis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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