uremia

uremia /ure·mia/ (u-re´me-ah)

1. azotemia; an excess of the nitrogenous end products of protein and amino acid metabolism in the blood.

2. the entire constellation of signs and symptoms of chronic renal failure.ure´mic

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u·re·mi·a or u·rae·mi·a (y-rm-)

n.

1. The accumulation of urinary waste products in the blood. Also called azotemia.

2. A toxic condition caused by uremia.

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u·remic adj.

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Uremia

The presence of excessive amounts of urea and other waste products in the blood.

Mentioned in: Alport Syndrome

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uremia

[yoo͡rē′mē·ə]

Etymology: Gk, ouron + haima, blood

the presence of excessive amounts of urea and other nitrogenous waste products in the blood, as occurs in renal failure. Also called azotemia. See also chronic glomerulonephritis, subacute glomerulonephritis. uremic, adj.

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uremia (yōō·rēˑ·mē·),

n the presence of increased amounts of urea and other nitrogenous waste products in blood. The condition typically results from renal failure. Also called
azotemia.

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uremia (ūrē´mē),

n the presence of urinary components in the circulating blood and the resultant symptoms. Manifestations include weakness, headache, confusion, vomiting, and coma, and in terminal chronic renal disease, purpura and epistaxis may be present. Uremia is caused by insufficient urinary excretion for any reason. See also stomatitis, uremic.

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uremia

1. an excess in the blood of urea, creatinine, and other nitrogenous end products of protein and amino acid metabolism; more correctly referred to as azotemia.

2. in current usage, the syndrome of chronic renal failure. As the glomerular filtration rate falls in either acute tubular necrosis or chronic renal failure, serum urea (usually expressed as blood urea nitrogen content, BUN) and creatinine rise to very high levels. However, BUN and creatinine measurements are only roughly correlated with the clinical signs of uremia. Other nitrogenous compounds present in small amounts may produce most of the toxic effects. Some uremic signs are due to losses of kidney function that do not involve azotemia.

Uremia is a syndrome that occurs as the end-stage in renal insufficiency. The pathology includes stomatitis, pneumonopathy, endocarditis and gastritis. In the dog and cat there is vomiting, diarrhea, anemia and sometimes ulcerative stomatitis. In horses there is depression and chronic diarrhea. Cattle show somnolence, depression and recumbency. Chickens develop visceral gout. Called also kidney failure.

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prerenal uremia

see azotemia.

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uremia

Prerenal azotemia, renal underperfusion Nephrology A constellation of Sx caused by the retention of urea and other products of protein catabolism due to inadequate kidney function in advanced renal failure Clinical N&V, pruritus, uremic frost, mental clouding, peripheral neuropathies, osteodystrophy, HTN, CHF, pericarditis, pulmonary edema Lab Acidosis, anemia, azotemia, ↓ Ca2+, ↑ PO₄, coagulopathy Pathogenesis 1º glomerular and/or tubular disease Management General support–restriction of protein, Na+, K+, and water; dialysis–hemodialysis, peritoneal dialysis; kidney transplant