upstream


Also found in: Dictionary, Thesaurus, Financial, Acronyms, Idioms, Encyclopedia, Wikipedia.

up·stream

(ŭp'strēm),
Refers to nucleic acid base sequences proceeding the opposite direction from expression.

upstream

In genetics, at a stage in the sequence of processes in the expression of a gene that is further away from the final protein product. The term is also used to mean in the direction of the 5'-end of a chain of bases in DNA (see PHOSPHODIESTER BOND). In both cases the opposite sense is called ‘downstream’.

upstream

(of a LOCUS on a DNA molecule) relating to a position in the opposite direction to that in which TRANSCRIPTION occurs, often before the transcription start site in DNA. By convention, the DNA sequence of genes is shown from 5′ (left) to 3′(right), so that if A is on the 5′ side of B, A is upstream of B. Compare DOWNSTREAM.

upstream

a term used in molecular biology to describe nucleotides of a nucleic acid molecule which lie in the 5′ direction from a particular reference point such as the site of initiation of transcription. See also downstream.

upstream activating site
DNA sequences that are upstream from the promoter and have a regulatory role in transcription.
References in periodicals archive ?
He has extensive experience across the financial, commercial and operational aspects of the upstream sector, and his insight and leadership will prove invaluable as we continue to invest in our global upstream portfolio.
As noted previously, there are two upstream firms manufacturing a homogeneous product with output levels [q.
According to industry sources, a group should never use an interest-bearing loan to cover the costs of buying an upstream business, because upstream enterprises always entail high risk.
To facilitate a new business model and realign the management structure, (1) S1, S2 and S3 each merged into P; (2) P transferred "almost all" of the former S1-S3 operating assets (contributions) to three newly formed corporations, new S1, new S2 and new S3 (transferees); and (3) S4 merged upstream into P in a statutory merger.
The Upstream Commerce Retail Intelligence Suite is ideally suited for Magento businesses with annual revenues of $1 million and above.
Market revenues and forecasts for upstream Processing of Biopharmaceuticals in the CMO market from 2009 to 2016.
The report " Russia Upstream Fiscal and Regulatory Report " sets out in detail the licensing framework under which firms must operate in the industry, clearly defining factors affecting profitability and quantifying the state's take from hydrocarbon production.
They'd like to shift it upstream, which is a nice way of putting it, but upstream means the Sepulveda Basin.
Upstream is a junior oil and gas exploration and Production Company whose specialty is identification and development for drilling world class offshore turbidite formations.
17, 2014 /PRNewswire/ -- Upstream Oil and Gas Quarterly Deals Review, Q2 2014 Summary GlobalData's "Upstream Oil and Gas Quarterly Deals Review, Q2 2014" report is an essential source of data and trend analysis on mergers and acquisitions (M&As) and financings in the upstream oil and gas industry.
LONDON, July 15, 2010 /PRNewswire/ -- Upstream, one of the world's largest mobile marketing solutions providers, (http://www.
Even though it makes the trip an upstream paddle, the journey is simple.

Full browser ?