unipolar disorder

Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to unipolar disorder: bipolar disorder, hypomania, depressive syndrome

unipolar disorder

major depression

A mental disorder characterised by severe depression lasting essentially without remission for at least two weeks, with symptoms that interfere with the ability to work, sleep, eat and enjoy once-pleasurable activities.
Clinical findings
Feelings of guilt, hopelessness, all-encompassing low mood accompanied by low self-esteem, persistent thoughts of death or suicide; difficulties in concentration, memory and decision-making capacity, behaviour (changes in sleep patterns, appetite, weight), physical well-being; persistent symptoms (e.g., headaches or digestive disorders) that do not respond to treatment; disabling episodic major depression can occur several times in a lifetime.

Patient discussion about unipolar disorder

Q. Bipolar depression And Unipolar depression Is bipolar depression different from unipolar depression?

A. Yes. These are two different disorders that are distinct in many ways: bipolar appears earlier (20's compared to middle aged), males and females are affected equally (depression is more prevalent among women), family tendency (more pronounced in bipolar) etc. The course is also different: bipolar have manic episodes, while depression includes only depressive episodes.

The treatment is also quite different (lithium and stabilizers for bipolar, SSRI for depression)

You may read more here:

More discussions about unipolar disorder
References in periodicals archive ?
Dose-response relationship between number of comorbid anxiety disorders in adolescent bipolar / unipolar disorders, and psychosis, suicidality, substance abuse and familiarity.
There's also a designation we use for recurrent episodes of depression without mania, which we call unipolar disorder.
Ying and his colleagues evaluated 355 patients experiencing an acute episode of unipolar disorder, 83 in the depressed phase of bipolar I disorder, and 77 in the depressed phase of bipolar II disorder.
Comorbidity for obsessive-compulsive disorder in bipolar and unipolar disorders.
Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other Axis I disorders, Biol Psychiatry, 1996; 39: 896-899