ugly


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A popular adjective for an aggressive disease or lesion
Infectious disease An ugly infection responds poorly to aggressive antibiotic therapy, which most commonly occurs in immunocompromised patients or those with terminal cancer
Oncology An ugly malignancy is characterised by fulminant clinical course, rapid deterioration, multiorgan failure, infection, and poor response to therapy
Pathology Ugly usually refers to a malignant lesion with bizarre, poorly differentiated cells characterised by marked nuclear atypia, pleomorphism, florid mitotic activity, and necrosis—e.g., giant cell tumour of the lung

ugly

A popular adjective for an aggressive disease or lesion Infectious disease An 'ugly' infection responds poorly to aggressive antibiotic therapy, which most commonly occurs in immunocompromised Pts or those with terminal CA Oncology An 'ugly' malignancy is characterized by fulminant deterioration, multiorgan failure, infection, poor response to therapy Surgical pathology 'Ugly' usually refers to a malignant lesion with bizarre, poorly differentiated cells characterized by marked nuclear atypia, pleomorphism and florid mitotic activity–eg, giant cell tumor of the lung. See Anaplasia.
References in periodicals archive ?
Steve Lewis, Coyote Ugly Franchisee and director of Coyote Ugly in Cardiff, will be opening the Manchester site.
To the "The Ugly American", the American way and interests were all that mattered and the "locals" had better toe the line.
Does that make her ugly or just independent or unconventional, especially if men are still attracted to her?
plpSellerId=Kmart&prdNo=1&blockNo=1&blockType=G1) Ugly Cardigan from Route 66.
On a book tour in South Africa, Donaldson was taken on safari and introduced to the Big Five (lion, leopard, rhino, buffalo and elephant), but found herself more intrigued by the Ugly Five, and so here they are in all their wrinkled, spindly, stinky, blood-flecked glory.
She told the Birmingham Post: "We were contacted from the official Coyote Ugly Saloon attorney in the US and were told that we were infringing on copyright laws.
The Coyote Ugly VP (Global Development) Justin Livingston disclosed, "Since launching our international franchise program last year, Coyote Ugly has made great strides in expanding to new markets across the world and this is another incredible milestone for the brand.
Mr Edge, Head of the Junior School said: "The story of the Ugly Duckling is very well-known and it is a lovely musical for our younger children to perform.
Therefore, all five cases show that an "ugly" name in fact indicated nothing ugly at all, but only the birth year of the name-bearer.
12 Dec 2015: Ugly Christmas Sweater Run (Colorado Springs)
Ugly in this context is more than just a suspense drama woven around the incidents that take place within the story.
The ugly Christmas sweater has become a ubiquitous feature of the holiday season,'' reports Time magazine, "on par with grumbling about Black Friday or wrestling with the Christmas lights.