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ubiquitin

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.01 sec.
u·biq·ui·tin (y-bkw-tn)
n.
A polypeptide found in all eukaryotic cells, including plant cells, that participates in a variety of cellular functions including protein degradation.

ubiquitin
[yo̅o̅bik′witin]
a small polypeptide that is involved in histone modification and is a marker for intracellular protein transport and degradation. It is found in all cells of higher organisms.

ubiquitin (yōōˈ·biˑ·kwi·tin),
n a 76-amino acid polypeptide from modification of histones; present in yeast and in most eukaryotic cells.

ubiquitin
heat shock (cell stress) protein present in mammalian cytosol; attaches to other cytosolic proteins and marks them for degradation either by specific proteases or by lysosomal enzymes.


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Genes involved in neuronal cell adhesion (including NRXN1, CNTN4, NLGN1, ASTN2) were enriched with copy number variation in ASD cases, compared with controls, as were genes involved in ubiquitin degradation (including UBE3A, PARK2, RFWD2, and FBXO40).
She said that, in humans, the SIAH ubiquitin ligases sit smack in the middle of the molecular pathway that leads to pancreatic cancer.
Genzyme Corporation (Cambridge, MA) has patented pDNA vectors containing the human cellular ubiquitin B (Ub) promoter.
 
 
 
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