type I collagen


Also found in: Acronyms, Wikipedia.

type I col·la·gen

the most abundant collagen, which forms large well-organized fibrils having high tensile strength.
References in periodicals archive ?
Of note, the thermal stability of soluble type I collagen extracted by limited pepsin digestion from DD palmar tissue was higher than that of normal aponeuroses, as shown by circular dichroism measurements.
The generation of type I collagen is a crucial step in bone formation where type I collagen is the major organic component of bone matrix.
Now, these rights have been expanded to include the use of regular, non-crosslinked, synthetic peptides mimicking amino acid sequences of the N-telopeptides of type I collagen, i.
FibroGen will also present an abstract describing the superior hemostatic ability of FibroGen's type III recombinant human collagen compared to bovine type I collagen when used in medical devices such as tissue sealants, hemostats and vascular sealants.
Osteomark(R) is a urinary assay that provides a quantitative measure of the excretion of cross-linked N-telopeptides of type I collagen (NTx), the manufacturing and commercializing rights of which are obtained under a license from Ostex International, Inc.
Cohesion Technologies (NASDAQ NM: CSON) today announced that the Company has demonstrated feasibility with its recombinant collagen technologies, having generated a thermally stable human Type I collagen and gelatin in yeast in a novel and proprietary form.
1988-509161, includes 11 claims directed to assay methods, antibodies, and test kits for measuring N-telopeptides of type I collagen (NTx) as an indication of human bone resorption.
5,455,179, covers a method of analyzing a body fluid sample for a type I collagen analyte (CTx) indicative of degradation of type I collagen in vivo.
This in vitro study reported a positive reaction of an N-telopeptides assay with skin collagen, indicating that the assay reacts generally with other type I collagen rather than being specific for bone collagen.
Pyrilinks is indicated for the detection of pyridinium crosslinks, a by-product of bone type I collagen resorption (loss), in urine, associated with metabolic bone diseases.
Nasdaq: MTRA) today announced receipt of marketing clearance from the US Food and Drug Administration (FDA) for two Pyrilinks(R) urine-based assays that provide a quantitative measure of the excretion of pyridinium crosslinks as an indicator of type I collagen resorption, especially bone collagen.