type I collagen


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type I col·la·gen

the most abundant collagen, which forms large well-organized fibrils having high tensile strength.
References in periodicals archive ?
These results that identify collagen from a waste source such as fish processing by-products have also been reported by Nagai and Suzuki (1999) who revealed that type I collagen could be isolated from fish skin bones and fins.
Of note, the thermal stability of soluble type I collagen extracted by limited pepsin digestion from DD palmar tissue was higher than that of normal aponeuroses, as shown by circular dichroism measurements.
Type I collagen gel induces Madin-Darby canine kidney cells to become fusiform in shape and lose apicalbasal polarity.
In individual children, this may coincide with the degradation of type I collagen occurring at the same time (releasing ICTP into the circulation), either as part of the normal saltatory growth pattern [25] or during subclinical infections that may affect short-term growth [26].
Now, these rights have been expanded to include the use of regular, non-crosslinked, synthetic peptides mimicking amino acid sequences of the N-telopeptides of type I collagen, i.
Initially, FibroGen is offering two of the 20 known human collagens through its web site: type I collagen and type III collagen.
Osteomark(R) is a urinary assay that provides a quantitative measure of the excretion of cross-linked N-telopeptides of type I collagen (NTx), the manufacturing and commercializing rights of which are obtained under a license from Ostex International, Inc.
Cohesion Technologies (NASDAQ NM: CSON) today announced that the Company has demonstrated feasibility with its recombinant collagen technologies, having generated a thermally stable human Type I collagen and gelatin in yeast in a novel and proprietary form.
1988-509161, includes 11 claims directed to assay methods, antibodies, and test kits for measuring N-telopeptides of type I collagen (NTx) as an indication of human bone resorption.
5,455,179, covers a method of analyzing a body fluid sample for a type I collagen analyte (CTx) indicative of degradation of type I collagen in vivo.
This in vitro study reported a positive reaction of an N-telopeptides assay with skin collagen, indicating that the assay reacts generally with other type I collagen rather than being specific for bone collagen.