type 2 diabetes mellitus


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type 2 diabetes mellitus

a type of diabetes mellitus characterized by insulin resistance in appropriate hepatic glucose production and impaired insulin secretion. Onset is usually after 40 years of age but can occur at any age, including during childhood and adolescence. Familial aggregation implies that genetic factors and environmental factors, such as obesity and a sedentary lifestyle, superimposed on genetic susceptibility are involved in the onset. The majority of persons with type 2 diabetes are obese; glucose tolerance is often improved by modest weight loss and increased activity. Persons with type 2 diabetes can manage their disorder with a meal plan, increased activity, oral antidiabetes agents such as insulin secretagogues, biguanides, alpha glucosidase inhibitors and insulin sensitizers, and insulin. Maturity onset diabetes of young is a rare type 2 diabetes, and an autosomal-dominant inheritance is clearly established. Previously called adult-onset diabetes, ketosis-resistant diabetes, maturity-onset diabetes, non-insulin-dependent diabetes mellitus, stabile diabetes. Also called type II diabetes mellitus. See also diabetes mellitus.

type 2 diabetes mellitus

Adult-onset diabetes, diabetes mellitus type 2, NIDDM, non-insulin-dependent diabetes mellitus Endocrinology A mild form of DM with an onset > age 40, ↓ incidence of DKA, accompanied by microvascular complications, which comprises 90% of DM; 80% of type 2 DM Pts are obese–an association known as 'diabesity', insulin-deficient, insulin-resistant Diagnosis
1. Fasting glucose is 7.8 mmol/L–US > 140 mg/dL on ≥ 2 occasions or.
2. When in a 75g GTT, the 2-hr and one other value–drawn at the 30, 60, or 90 min intervals are > 11.2 mmol/L–US > 200 mg/dL Clinical Blurred vision, poorly healing cuts, paresthesias in hands/feet, recurring skin, mouth, or bladder infections, any type 1 Sx–thirst, ↑ appetite, rapid weight loss, fatigue  Treatment type 2 DM does not usually require exogenous insulin; insulin may be required during 'crises' Prognosis Relatively good, especially if controllable by lifestyle modifications. See Glucose tolerance curve, MODY. Cf type 1 DM.

Type 2 diabetes mellitus

One of the two major types of diabetes mellitus, characterized by late age of onset (30 years or older), insulin resistance, high levels of blood sugar, and little or no need for supple-mental insulin. It was formerly known as adult-onset or non-insulin-dependent diabetes.
Mentioned in: Insulin Resistance

type 2 diabetes mellitus (formerly known as non-insulin-dependent diabetes mellitus [NIDDM] or maturity-onset diabetes)

chronic-onset disease often presenting in middle to old age (peak age of onset = >35 years); characterized by increasing insulin resistance (subject releases normal/raised amounts of insulin from pancreatic β cells, but insulin does not react with insulin receptors of peripheral tissue cells; intracellular reactions are impoverished/absent due to unavailability of intracellular glucose; patients present with symptoms similar to type 1 diabetes (polyuria, polydypsia and glycosuria; dehydration and tiredness; history of recurrent infections; dyslipidaemia), but are characteristically overweight and hypertensive, with hypercholesterolaemia; symptom onset is gradual, sometimes extending over years; patients may remain undiagnosed until secondary pathologies (due to micro- and macrovascular disease) develop, e.g. coronary artery disease, stroke, peripheral vascular disease, eye disease, renal dysfunction, painless foot ulceration and foot infections; type 2 diabetes patients are treated by strict dietary control, oral hypoglycaemic drugs, and insulin supplementation for life as necessary (contrast with maturity-onset diabetes of the young)

Patient discussion about type 2 diabetes mellitus

Q. Type 2 Diabetics solution My uncle is suffering from type 2 diabetics and i want to know that is there any permanent solution for type 2 diabities. Very worried about weight loss too. Any one there to give us a permanent solution?

A. Type 2 diabetes is due to improper use of insulin or insulin resistance.

There is a web site given below which provides information on alternative medicines for diabetes. Alternative medicines - ayurveda herbs, homeopathy, yoga and acupressure treatments.
http://healthy-ojas.com/html/diabetes_mellitus.html
http://healthy-ojas.com/html/alternative_medicine_diabetes.html

Q. Women with diabetes are in general found with type 1 or with type 2 diabetes during pregnancy and why?

A. Women develop gestational diabetes during pregnancy and after pregnancy the gestational diabetes goes, if not this gestational diabetes has chances to develop into type 2 diabetes. A pregnant woman can also have type 1 and 2 diabetes equally and during pregnancy she may get gestational diabetes.

Q. Is Diabetes type 2 a chronic disease? I have been diagnosed with Diabetes; does this mean I will always have it from now on?

A. I was a type 2 diabetic for 15 years. I had a gastric bypass, lost a ton of weight and no longer test as a diabetic. But, my doctors say "once a diabetic, always a diabetic." So the tendency is still there and must be addressed always. My problem is not evident but now I have kidney disease and it is attributed to diabetes with complications. Eat right, get exercise and lose weight. I hope you educe your numbers so you won't risk the complications. This is your best goal for now. Diabetes is being constantly researched, so the future looks bright and maybe a cure is on the horizon! Blessings!

More discussions about type 2 diabetes mellitus
References in periodicals archive ?
Sodium-glucose co-transporter 2 inhibitors for the treatment of type 2 diabetes mellitus.
All patients of type 2 diabetes mellitus who were visiting the diabetes clinic were enrolled for the study after taking informed written consent.
A study in Faisalabad indicated that women with type 2 diabetes mellitus has significantly high level of stress than men with Type 2 diabetes mellitus10.
A total of sixty-nine patients with type 2 diabetes mellitus fulfilling WHO criteria along with age and sex matched controls with no history of diabetes mellitus or thyroid dysfunction were enrolled from Military Hospital, Rawalpindi and Informed consent was obtained from each participant.
Demographic comparison of subjects with normal blood glucose level and patients with type 2 diabetes mellitus
Jake was diagnosed with Type 2 diabetes mellitus, and his management plan was initiated.
Emerging combination treatments containing insulin may be useful in addressing unmet needs in the management of type 2 diabetes mellitus, and introduction at an early stage could potentially allow early aggressive therapy approaches to optimise long-term treatment outcomes3.
This study revealed that audiovisual reaction time was prolonged in patients with type 2 diabetes mellitus when compared to healthy control group, as shown in Table 1.
Prevalence of type 2 diabetes mellitus in hepatitis C virus infected population: a study.
It is found that Vitamin D deficiency was more prevalent and severe in Type 2 diabetes mellitus patients as compared to the nondiabetic subjects.
ISLAMABAD -- Mediterranean diet lowers the risk of a condition associated with hypertension, type 2 diabetes mellitus, arthritis, and cardiovascular diseases, a new research has claimed.
We faithfully read the article "General and Gender Characteristics of Type 2 Diabetes Mellitus Among the Younger and Older Age Groups" written by Samir Burhanaldin Al-Mukhtar et al.