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1. transient abnormal enlargement of a body part or area not due to cell proliferation; see also edema. Called also tumefaction, tumescence, and turgescence.
cloudy swelling a term formerly used for an early stage of toxic degeneration of protein constituents of organs in infectious diseases, when the tissues appear swollen and opaque but revert to normal when the cause is removed.


1. A swelling. Synonym(s): tumentia
2. Synonym(s): tumescence
[see tumefacient]


/tu·me·fac·tion/ (-fak´shun) swelling.


(to͞o′mə-făk′shən, tyo͞o′-)
a. The act or process of puffing or swelling.
b. A swollen condition.
2. A puffy or swollen part.

tu′me·fac′tive (-tĭv) adj.


1. A swelling.
2. Synonym(s): tumescence.


a swelling; the state of being swollen, or the act of swelling; puffiness; edema.

Patient discussion about tumefaction

Q. How can we avoid swelling in the legs?

A. it really depends what the cause is- there are 219 different causes, not all of them have the same treatment..you will have to be more specific.
here is a site that helps me a lot, maybe you'll find it useful :)

Q. What Causes ankle Swelling? My son woke up this morning with a red, swollen ankle. What could cause this situation?

A. A swollen and red ankle suggest either a traumatic injury to the joint or an infection in the joint, adjacent tissues or bones. This is an emergency and it is important to consult a doctor as soon as possible, especially if the joint loses its ability to perform movements in all directions.

Q. can flights cause swelling of the legs? is it normal? is it dangerous? i took a flight from London to N.Y.C a week ago and my ankles looked like two red blimps afterwards and it was painful walking on them later.

A. i think that you got acquainted with my old friend-"Economy class syndrome".. i got it while flying to Australia. this is not normal- this is what happens when a clot of blood forms in your veins (usually legs) and stops blood flow back to the heart. if you already have problems with blood coagulation - your Dr. should have told you to be careful while flying. if not- you got an early call and should check it out. CNN did a story on that, i found you a link:

More discussions about tumefaction
References in periodicals archive ?
Treatment for tumefactive fibroinflammatory lesions may include surgery, radiation, corticosteroids, or a combination of these.
Keywords * Tumefactive fibroinflammatory lesion * Sinus * Neoplasms
Tumefactive Cerebral Amyloid Angiopathy Mimicking CNS Neoplasm.
These findings solidified the suspicion of Tumefactive MS.
In their study of 20 cases, the most common forms were the infiltrative (50%) and tumefactive (33%).
Lesions may rarely be presented as isolated enlargements of parenchymal tumefactive mass that may imitate neoplasms [9, 10].
Dermatological examination revealed multiple oedematous, tumefactive nodular lesions that had smooth margins and were 4-15 mm in diameter with surrounding erythema and partial crusting on the flexor side of the right wrist (Figure).
Tumefactive multiple sclerosis (MS) is a rare variant of MS.
RADIOLOGIC DIAGNOSIS: Tumefactive multiple sclerosis.