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tubulointerstitial nephritis

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia, Hutchinson 0.02 sec.
nephritis /ne·phri·tis/ (nĕ-fri´tis) pl. nephri´tides   [Gr.] inflammation of the kidney; a focal or diffuse proliferative or destructive disease that may involve the glomerulus, tubule, or interstitial renal tissue.
glomerular nephritis  glomerulonephritis.
interstitial nephritis  primary or secondary disease of the renal interstitial tissue.
lupus nephritis  glomerulonephritis associated with systemic lupus erythematosus.
potassium-losing nephritis  see under uropathy.
radiation nephritis  kidney damage caused by ionizing radiation; symptoms include glomerular and tubular damage, hypertension, and proteinuria, sometimes leading to renal failure. It may be acute or chronic, and some varieties do not manifest until years after the radiation exposure.
salt-losing nephritis  see under nephropathy.
transfusion nephritis  nephropathy following transfusion from an incompatible donor.
tubulointerstitial nephritis  nephritis of the renal tubules and interstitial tissues, usually secondary to drug sensitization, systemic infection, graft rejection, or autoimmune disease. An acute type and a chronic type have been distinguished.

tu·bu·lo·in·ter·sti·tial nephritis (tby-l-ntr-stshl)
n.
Nephritis affecting renal tubules and interstitial tissue, characterized by infiltration by plasma cells and mononuclear cells and seen in lupus nephritis, allograft rejection, and methicillin sensitization.


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