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agglutination |
Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson | 0.04 sec. |
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agglutination /ag·glu·ti·na·tion/ (ah-gloo?ti-na´shun) 1. the action of an agglutinant substance. 2. the process of union in wound healing. 3. the clumping together in suspension of antigen-bearing cells, microorganisms, or particles in the presence of specific antibodies (agglutinins).agglu´tinative cross agglutination the agglutination of particulate antigen by antibody raised against a different but related antigen; see also group a. group agglutination agglutination of members of a group of biologically related organisms or corpuscles by an agglutinin specific for that group. intravascular agglutination clumping of particulate elements within the blood vessels; used conventionally to denote red blood cell aggregation.
agglutination ( n the aggregation or clumping together of cells as a result of their interaction with specific antibodies called agglutinins, commonly used in blood typing and in identifying or estimating the strength of immunoglobulins or immune sera. agglutination aggregation of separate particles into clumps or masses; especially the clumping of bacteria or blood cells by antibody specific to, or directed against, surface antigenic determinants. See also agglutinin. bacterial agglutination test a diagnostic procedure that employs serum or other body fluid of unknown antibody titer, titrated with standard suspension of bacteria as antigen. These may be performed quantitatively in 96-well microtitration plates or qualitatively on slides. cross agglutination the agglutination of particulate antigen by an antibody raised against a different but related antigen; see also group agglutination (below). group agglutination agglutination—usually to a lower titer—of various members of a group of biologically related organisms by an agglutinating antibody made to one of that group. intravascular agglutination clumping of particulate elements within the blood vessels; used conventionally to denote red blood cell agglutination. latex agglutination test see passive agglutination test (below). microscopic agglutination test one in which the test mixtures are examined microscopically to detect the agglutination. mucus agglutination test see mucus agglutination test. passive agglutination test an agglutination reaction in which a soluble antigen, such as gonadotropin, is linked to inert particles such as latex beads or tanned erythrocytes. platelet agglutination the clumping together of platelets owing to the action of platelet agglutinins. Such agglutinins are important in platelet typing. slide agglutination test a rapid screening or semiquantitative test in which antibody and antigen are mixed on a glass slide and observed for agglutination. agglutination test see bacterial agglutination test (above). tube agglutination test an agglutination test for the identification of bacteria carried out in a test tube, a positive reaction consisting of a clearing of a prior opalescence. |
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