trypsinogen


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trypsinogen

 [trip-sin´o-jen]
the inactive precursor of trypsin, secreted by the pancreas and activated to trypsin by contact with enterokinase.

tryp·sin·o·gen

, trypsogen (trip-sin'ō-jen, trip'sō-jen),
An inactive protein secreted by the pancreas that is converted into trypsin by the action of enteropepsidase.
Synonym(s): protrypsin

trypsinogen

/tryp·sin·o·gen/ (trip-sin´o-jen) the inactive precursor of trypsin, secreted by the pancreas and activated in the duodenum by cleavage by enteropeptidase.

trypsinogen

(trĭp-sĭn′ə-jən)
n.
The inactive precursor of trypsin, produced by the pancreas and converted to trypsin in the small intestine by enterokinase.

trypsinogen

[tripsin′əjən]
Etymology: Gk, tripsis + genein, to produce
the inactive precursor form of trypsin. Trypsinogen is secreted in pancreatic juice and converted to active trypsin through the action of enterokinase in the intestine. Also called protrypsin.

tryp·sin·o·gen

, trypsogen (trip-sin'ō-jen, trip'sō-jen)
An inactive protein secreted by the pancreas that is converted into trypsin by the action of enteropeptidase.

trypsinogen

The precursor of TRYPSIN produced by the pancreas that is converted into the active form, trypsin, when acted upon by the enzyme enterokinase in the small intestine.

trypsinogen

see TRYPSIN.

trypsinogen

the inactive precursor of trypsin, secreted by the pancreas and activated to trypsin by contact with enterokinase.
References in periodicals archive ?
Excessive drinking of alcohol and intake of high fat foods cause cholecystokinin receptor (CCKR) signaling pathways to induce intra-acinar activation of trypsinogen.
By the present invention, trypsinogen is converted to trypsin and chymotrypsinogen to chymotrypsin by pre-activation to a maximum and is then dried and defatted simultaneously as hereinafter described, while this high enzymatic activity is held substantially without change, to produce highly active raw powders equal in activity to the fresh gland.
The signatures of trypsinogen in the antifreeze are quite clear at the two ends," says DeVries.
Efficacy of statewide neonatal screening for cystic fibrosis by assay of trypsinogen concentrations.
Interestingly, this has been shown to be associated with similar molar concentrations of tumor-associated trypsinogen-1 and -2 (11), which led to the assumption that SPINK1 plays a similar protective role against trypsinogen activation in ovarian tumors as it does in the pancreas (12).
6) familial adenomatous polyposis and 7) hereditary pancreatitis with germline mutations in the cationic trypsinogen gene.
Studies of an anionic trypsinogen and its active enzyme from porcine pancreas.
Hereditary pancreatitis: clinical features and inheritance characteristics of the R122C mutation in the cationic trypsinogen gene (PRSS1) in six Spanish families.
National programs to identify CF patients using circulating immunoreactive trypsinogen (IRT) exist in England, Scotland, France, Wales, Northern Ireland, New Zealand, and Australia.
Trypsinogen and chymotrypsinogen in the homogenates were activated with enterokinase at a concentration of 4 mg/ml and incubated at 4[degrees]C for 24 h.
The combination of an acidotic environment and free fatty acids causes activation of trypsinogen, initiating acute pancreatitis.
Many trypsinogen mutations, mutations in the cystic fibrosis transmembrane regulator genes, and familial hypertriglyceridemia can cause pancreatitis.