New insights into trypanosomatid
U5 small nuclear ribonucleoproteins.
However, despite its transmission of trypanosomatid
parasites to the plants, it is not clear if the insect is able to reproduce on them or not.
Docampo and Moreno  report that some bisphosphonate compounds inhibit the growth of trypanosomatid
parasites including Leishmania donovani both in vitro and in vivo.
Several natural products have showed to be as selective trypanothione reductase inhibitors in previous studies involving parasites of trypanosomatid
class (Gallo et al.
aquaporins: roles in physiology and drug response.
The New Medicine for Trypanosomatid
Infections (NMTrypI) consortium uses a highly interdisciplinary approach to optimize pteridine, benzothiazole and miltefosine derivatives, as well as natural products against Trypanosomatids
protozoan parasites comprise genus of Trypanosoma and Leishmania that cause neglected tropical diseases.
Expression of human tissue plasminogen activator in the trypanosomatid
protozoan Leishmania tarentolae.
1989) Glucosylation of glycoproteins by mammalian, plant, fungal, and trypanosomatid
protozoa microsomal membranes.
On the other hand, picolinic acid is a structural analogue of nicotinic acid (3-pyridinecarboxylic acid) and nicotinamide which are supplied in chemically defined medium for trypanosomatid
growth (MELO et al.
Nussbaum K, Honek J, Cadmus CM, Efferth T (2010) Trypanosomatid
parasites causing neglected diseases.
Gannavaram S, Vedvyas C, Debrabant A, Conservation ofthe pro-apoptotic nuclease activity of endonuclease G in unicellular trypanosomatid