pancytopenia /pan·cy·to·pe·nia/ (-sīt-ah-pe´ne-ah) abnormal depression of all the cellular elements of the blood.
pancytopenia
pancytopenia
pan·cy·to·pe·ni·a (p n s -t -p  n-)n. A pronounced reduction in all of the formed elements of the blood. |
pancytopenia
[pan′sītəpē′nē·ə]
Etymology: Gk, pan + kytos, cell, penia, poverty
marked reduction in the number of red blood cells, white blood cells, and platelets. See also anemia, aplasia, neutropenia. pancytopenic, adj.
pancytopenia
abnormal depression of all the cellular elements of the blood. Results from the depression of activity of bone marrow, spleen and lymph nodes such as occurs in radiation injury and a number of poisonings, e.g. Pteridium aquilinum, trichlorethylene extracted soybean meal, nitrofurans and stachybotrytoxicosis.
myelophthisic pancytopenia
resulting from loss of bone marrow function.
tropical canine pancytopenia
see canine ehrlichiosis.
pancytopenia
Hematology A global ↓ of 'blood cells' with hypoplasia or aplasia of hematopoietic precursors in BM–eg, hypoplastic myelodysplasia Etiology Aplastic anemia–drug-related, especially in chemotherapy,
RT, toxins, BM replacement by hematopoietic, lymphoproliferative and metastatic CA, storage diseases, osteopetrosis, myelofibrosis, hypersplenism–congestive splenomegaly, hematopoietic malignancy, storage diseases, sarcoidosis, malaria,
kala-azar, infection–eg, fungemia, septicemia, TB, megaloblastic anemia. See Fanconi's disease.
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