trisomic


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to trisomic: monosomic

tri·so·mic

(trī-sō'mik),
Relating to trisomy.

tri·so·mic

(trī-sō'mik)
Relating to trisomy.

trisomic

(tri-som'ik)
In genetics, an individual possessing 2n+1 chromosomes, that is, one set of chromosomes contains an extra (third) chromosome.
See: chromosome; karyotype
References in periodicals archive ?
Using the above information, researchers led by Catherine Spong at the National Institutes of Health in Bethesda, Maryland, injected NAP and SAL into mice pregnant with trisomic pups in the middle of their pregnancy.
Interestingly, studies performed on human trisomic tissues indicate that only a subset of HSA21 genes is over-expressed relative to euploid controls and that the increase in expression may be different from the expected ~1.
First, there is a prevalence of trisomics (hyperploidy) over monosomics (hypoploidy) among spontaneous abortions and liveborns (Hecht and Hecht, 1987).
Three DNA fragments, visualized as peaks of approximately the same height in an electropherogram, or peak ratios of 2:1 and 1:2, are indications that the sample is in the trisomic range.
Taking the data obtained from the chromosome 21NAME project as a point of departure, it was possible to explore the percentage of methylation of CpG islands in normal fibroblasts and compare it to that of trisomic fibroblasts.
Chromosomally aberrant progeny of selfed trisomic Eleocharis erythropoda Steud.
Posiphen reduces the rate of synthesis of APP in cell cultures, normal, transgenic and trisomic mice.
Inversion duplication of chromosome 6 with trisomic codominant expression of HLA antigens.
In cell cultures, normal, transgenic and trisomic mice Posiphen lowers amyloid- precursor protein (APP) levels by inhibiting the rate of APP messenger RNA synthesis.
The actual increase caused by the trisomic fetus will be, on average, one half of whatever the percent fetal DNA contribution is in that sample.
The precise chromosomal position of Rph5 is not known, although the gene was assigned to chromosome 3H by trisomic analysis (Tan, 1978; Tuleen and McDaniel, 1971).