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trifluridine

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trifluridine /tri·flur·i·dine/ (-floor´ĭ-dēn) an antiviral compound that interferes with viral DNA synthesis, used topically in the treatment of keratitis and keratoconjunctivitis caused by human herpesviruses 1 and 2.
trifluridine [tri-floor´ĭ-dēn]
an antiviral compound that interferes with viral DNA synthesis, used topically in the treatment of keratitis and keratoconjunctivitis caused by human herpesviruses 1 and 2.

trifluridine (ophthalmic) (trī´floor´-idēn´ ofthal´mik),
n brand name: Viroptic ophthalmic solution;
drug class: antiviral;
action: inhibits viral deoxyribonucleic acid (DNA) synthesis and replication;
uses: treatment of primary keratoconjunctivitis, recurring epithelial keratitis, and keratitis associated with herpes simplex virus types 1 and 2.

trifluridine
an antiviral agent used topically in the treatment of herpesvirus infections of the eye.


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The patient was started on trifluridine and bacitracin ointments, broad-spectrum systemic antimicrobial agents, and pain medication; she was admitted to the hospital.
In studies of mice infected with the virus, topical application of the drug proved as effective as trifluridine, the currently approved topical drug for human ocular herpesvirus infection.
In addition to marketing Acyclovir, Schein manufactures and markets another anti-viral product, Trifluridine Ophthalmic Solution, the only available generic formulation comparable to Glaxo Wellcome's Viroptic(R).
 
 
 
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