That's the implication of the first study to probe the genetic makeup and evolutionary relationships of strains of bacteria, known as treponemes, that cause syphilis and related diseases.
Harper's team isolated 21 genetic regions from 26 strains of treponemes found in various parts of the world.
Negative darkfield: Either no treponemes
found or spiral organisms seen but without the characteristics of T pallidum.
Additional studies of the risk of transfusion-related syphilis are planned, and will address how often and how many infectious treponemes
are found in blood products from those with early syphilis, and how likely the treponemes
are to survive processing.
Use of PCR for identification of TP in CSF has been disappointing, due to inadequate sensitivity and the inability to distinguish between pathogenic and nonviable treponemes
An immunologic test had previously located signs of treponemes
on one bone from the bear.
Noting that the earliest reports of syphilis and related diseases did not appear in the Old World until after 1500, many scientists have suggested that Columbus's crew and other voyagers might have carried treponemes back with them when they returned from from the New World.
3 NATURE, scientists report that, using antibodies specific to treponemes, they successfully identified treponemal material on the bear's bones.
may be limited from sanctuary sites such as the CNS.
The histologic examination of umbilical cords from infants born to mothers with syphilis demonstrated the following: seven cords (11%) with marked funisitis, necrosis (necrotizing funisitis) and treponemes (five by IHC and DFA; two by IHC only); marked funisitis without necrosis or spirochetes in three (4%) cases; mild funisitis in 18 (27%) cases; and no histopathologic abnormality in 38 (58%) cases.
Inflammation, necrosis, and treponemes in umbilical cords from infants with congenital syphilis, Bolivia