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transthyretin

   Also found in: Acronyms, Wikipedia 0.01 sec.
transthyretin /trans·thy·re·tin/ (-thi-ret´in) an α-globulin secreted by the liver that transports retinol-binding protein and thyroxine in the blood. Numerous mutations have been associated with the ATTR form of familial amyloidosis.
transthyretin
Prealbumin A 55 kD homotetrameric protein that binds thyroxine and retinol; transthyretin is ↓ in malnutrition and in acute and chronic inflammation, and thus is considered a 'negative acute phase protein', which may be defective in AD amyloidosis. Cf Proalbumin.


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Basically, they found an association between cell phone use and an increased amount of a protein called transthyretin in the blood.
Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.
Hawkins, National Amyloidosis Centre, Division of Medicine, and University College London Medical School Royal Free Hospital, will discuss transthyretin (TTR)-mediated amyloidosis.
 
 
 
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