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transthyretin

   Also found in: Acronyms, Wikipedia 0.02 sec.
transthyretin /trans·thy·re·tin/ (-thi-ret´in) an α-globulin secreted by the liver that transports retinol-binding protein and thyroxine in the blood. Numerous mutations have been associated with the ATTR form of familial amyloidosis.
transthyretin
Prealbumin A 55 kD homotetrameric protein that binds thyroxine and retinol; transthyretin is ↓ in malnutrition and in acute and chronic inflammation, and thus is considered a 'negative acute phase protein', which may be defective in AD amyloidosis. Cf Proalbumin.


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