transposition of great vessels

transposition /trans·po·si·tion/ (trans″po-zish´un)

1. displacement of a viscus to the opposite side.

2. the operation of carrying a tissue flap from one situation to another without severing its connection entirely until it is united at its new location.

3. the exchange of position of two atoms within a molecule.

transposition of great vessels a congenital cardiovascular malformation in which the position of the chief blood vessels of the heart is reversed. Life then depends on a crossflow of blood between the right and left sides of the heart, as through a ventricular septal defect.

transposition of great vessels

A congenital cardiovascular malformation in which the aorta arises from the right ventricle while the pulmonary artery arises from the left ventricle.

transposition [trans″po-zish´un]

displacement to the opposite side; in genetics, the nonreciprocal insertion of material deleted from one chromosome into another, nonhomologous chromosome.

transposition of great vessels a congenital heart defect in which the position of the chief blood vessels of the heart is reversed, so that the aorta arises from the right ventricle instead of the left and the pulmonary artery emerges from the left ventricle rather than from the right. The result is that oxygen-poor blood returning from the systemic circulation to the right side of the heart gets pumped back into the general circulation instead of being transported to the lungs, and oxygen-rich blood flows aimlessly to and from the lungs. The condition may be corrected by surgery.

Complete transposition of great arteries.

Transposition of great arteries Pediatric surgery A congenital cyanotic heart defect in which the position of the aorta and pulmonary artery is transposed; absence of a communication between the pulmonary circulation and the systemic circulation is fatal; usually there is an associated defect that permits mixing of the systemic and pulmonary circulation to provide oxygenated blood to the body Prenatal risk factors Maternal rubella or other viral illnesses during pregnancy, poor prenatal nutrition, maternal alcoholism, maternal age > 40, DM Clinical Early onset of cyanosis, SOB. See Congenital heart disease.

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