transpeptidation


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trans·pep·ti·da·tion

(trans'pep-ti-dā'shŭn),
A reaction involving the transfer of one or more amino acids from one peptide chain to another, as by transpeptidase action, or of a peptide chain itself, as in bacterial cell wall synthesis.

transpeptidation

[-pep′tidā′shən]
the transfer of an amino acid from one peptide chain to another.

trans·pep·ti·da·tion

(trans-pep'ti-dā'shŭn)
A reaction involving the transfer of one or more amino acids from one peptide chain to another, as by transpeptidase action, or of a peptide chain itself, as in bacterial cell wall synthesis.
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References in periodicals archive ?
While in the presence of B-lactam antibiotics, normal PBPs are blocked, PBP2a precedes the transpeptidation reactions, thereby results in normal cell wall synthesis (8), (10).
beta]-lactiun antibiotics such as methicillin bind to proteins responsible for bacterial cell wall synthesis by a mechanism known as transpeptidation (peptidase enzymes also known as penicillin binding proteins, PBP); thus, if PBP is altered, the [beta]-lactam antibiotic cannot inhibit cell wall formation and the strain is rendered resistant.
PBPs catalyze the final step of polymerization (transglycosylation) and cross-linking by transpeptidation of peptidoglycan.