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translocation Down syndrome

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translocation Down syndrome
n.
A condition in which, as a result of translocation of a large segment of chromosome 21 to another chromosome, an individual has virtually the genetic equivalent of three chromosomes 21 and thus has the phenotype of Down syndrome but with the normal number of chromosomes.


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Children with translocation Down syndrome have the usual two copies of chromosome 21, but they also have additional material from chromosome 21 stuck to the translocated chromosome.
 
 
 
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