transfusion trigger

transfusion trigger

Transfusion threshold Transfusion medicine The Hct and Hb values at or below which packed red cells are usually ordered for transfusion by a clinician; the most widely used current TT is a Hb of 70 g/L, after an NIH consensus = conference; lower TTs–eg, transfusion at 7g Hb, have better outcomes–eg, ↓ MIs and ↓ pulmonary edema 'Prophylactic' platelet TT Stable Pts < 5 x 109, Pts with recent hemorrhage and/or temperature ≥ 38.5º C < 10 x 109, Pts with significant coagulopathy, anatomic lesion(s), or heparin therapy < 20 x 109 'Therapeutic' platelet TT Active hemorrhage or scheduled invasive procedure < 50 x 109, hemorrhage and/or thrombocytopenia, prn

transfusion trigger

A colloquial term for the point at which the risks associated with low hematocrit or hemoglobin levels outweigh the risks of adverse reactions associated with a blood transfusion.

Patient care

The concept of a transfusion trigger is controversial. Some medical authorities recommend transfusions only for patients who are actively compromised by bleeding rather than to adjust for specific levels of hemoglobin or hematocrit. Risks also include those associated with infectious diseases.

References in periodicals archive ?
The 10-30 rule for transfusion trigger was questioned by the 1999 study of Hebert et al.
In uncomplicated anaemia, transfusion trigger is 7-8 gm/dL [8]; however, it is largely to the discretion of the treating doctor to change the trigger based on the comorbidities of the patient.
The publication of the TRICC (Transfusion Requirements in Critical Care) trial in 1999 showed that a restrictive approach to the use of red cell concentrates (RCCs) with a low haemoglobin (Hb) trigger of <8 g/dL had no harmful clinical effects and clinical outcomes were similar to those in patients treated with a more liberal transfusion regimen with the transfusion trigger set at 10 g/dL.
Other studies [25] recommend transfusion trigger for the restoration of the lost circulatory volume with RES.
Methods: From June 2013 to June 2014, patients were randomly divided into the experimental group (Peri-operative Transfusion Trigger Score of Emergency [POTTS-E] group) and the control group (control group).
LBA-6 Transfusion trigger trial for functional outcomes in cardiovascular patients undergoing surgical hip fracture repair (FOCUS): The principle results.
10 More often, a hospital-wide transfusion trigger policy is in place that may support transfusions at very conservative hemoglobin concentrations.
In stable HIV-infected anaemic children, it is reasonable to consider a Hb <6 g/dl as the transfusion trigger.
Even in the presence of ischaemic heart disease, in the absence of ongoing bleeding, a transfusion trigger greater than 90 g/l is rarely indicated.
The SIGN guidelines (SIGN 2001) have suggested a transfusion trigger of 7g.
Patients will be randomized at the time a blood transfusion is deemed necessary according to a defined transfusion trigger.
Should the transfusion trigger and hemoglobin low critical limit be identical?

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