transformation

transformation /trans·for·ma·tion/ (trans″for-ma´shun)

1. change of form or structure; conversion from one form to another.

2. in oncology, the change that a normal cell undergoes as it becomes malignant.

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bacterial transformation  the exchange of genetic material between strains of bacteria by the transfer of a fragment of naked DNA from a donor cell to a recipient cell, followed by recombination in the recipient chromosome.

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trans·for·ma·tion (trnsfr-mshn)

n.

1. See metamorphosis.

2. The genetic alteration of a bacterial cell by introduction of DNA from another cell or from a virus.

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transformation

[-fôrmā′shən]

Etymology: L, transformare, to change shape

the integration of exogenous genes into chromosomes in a form that is recognized by the replicative and transcriptional apparatus of the host cell. Transformation occurs rarely in most cell populations.

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transformation

change of form or structure; conversion from one form to another. In oncology, the change that a normal cell undergoes as it becomes malignant. In statistics a functional change to the variable.

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bacterial transformation

the process of intercellular transfer of genetic information in which a small portion of the total DNA of a lysed bacterium enters a related bacterium and is incorporated into the DNA genome of the recipient.

cell transformation

the changes in types of proteins expressed and growth characteristics that take place in cells infected by some viruses, including tumor formation by retroviruses.

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transformation

Oncology Malignant transformation The change that a normal cell undergoes as it becomes malignant, either due to infection with an oncogenic virus or environmental factors. See Malignant transformation, Progressive transformation of germinal centers, Linear transformation, Sol-gel transformation.