In contrast, trans-crocetin permeates in a concentration-independent manner (10-114 [micro]M) the intestinal barrier by transcellular
passage with about 32% of the substrate being transported within 2 h and a permeation coefficient of [P.
1991) due to expeditious loss of Ca by milk synthesis, and less efficiency of Ca absorption by the intestinal transcellular
pathway (Horst et al.
Tight junctions between the cells of the BBB endothelium form a physical barrier, significantly reducing passive diffusion through the paracellular pathway, and forcing any molecular traffic to occur mainly across the endothelial transcellular
Exosomes account for vesicle-mediated transcellular
transport of activatable phospholipases and prostaglandins.
Long considered as inert debris, MPs are now appreciated as an important transcellular
delivery system in the exchange of biological signals.
Measurement of transcellular
fluid shift during haemodialysis.
Instead, he reviewed four ways that ingredients could penetrate beyond the outer layer of the skin: sweat glands, hair follicles, and intercellular and transcellular
Most of the work on human and mouse (or murine) CF in the late 1990s suggested that the loss of CFTR elevated the salt concentration in CF airway surface liquid and in sweat by related mechanisms, with the elevated sodium chloride concentration due to a block in transcellular
But the transport of glucose showed an increase in their experiments which was attributed to changes in passive transcellular
Two potential micro-routes of entry exist, the transcellular
(or intracellular) and the intercellular pathways (Figure-2).
Iverson L, Kristensen P, Gron B, Ziboh VA, Kragbelle K: Human epidermis transforms exogenous leukotrien A4 in to peptide leukotriens: possible role in transcellular
2,27,28) Deferiprone is rapidly absorbed from the gastrointestinal tract via the transcellular
pathway and has an absorption half-life of 1-32 minutes in humans.