The BCKD complex is composed of four subunits named E1a, E1[beta], E2, and E3, around a cubic core of 24 identical dihydrolipoyl transacylase
subunits of E2, encoded by the DBT gene (10).
2] family, is C-terminally farnesylated and possesses lysophospholipase and transacylase activities in addition to [PLA.
PNPLA1 acts as a unique transacylase, catalyzing the transfer of linoleic acid (LA; C18:2) in triglyceride to the [omega]-hydroxy residue of ultra-longchain fatty acid in ceramide to form [omega]-O-acylceramide, a lipid component essential for skin barrier function.
2005) Identification of a novel keratinocyte retinyl ester hydrolase as a transacylase and lipase.
Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A(2) family members possessing triacylglycerol lipase and acylglycerol transacylase
Patent 6,287,835 "Transacylases
of the paclitaxel biosynthetic pathway," protects the use of certain transacylase
genes to improve or produce paclitaxel and intermediates of the paclitaxel pathway such as baccatin.
The LPL activity was stronger than the PLB activity and the transacylase activity was also detected.
2], the activities and substrate specificities of PLB are not so strict and sometimes it shows lipase, esterase, and/or transacylase activities at different degree of activity.
1], transacylase, lipase and acylesterase activities are also found, all of which are inhibited by DFP.
The gene product of the TAZ gene is a transacylase
involved in the remodeling of cardiolipin (CL) (12-14), and its deficiency results in the most consistent biochemical abnormality: decreased CL levels and increased monolysocardiolipin (MLCL) content (15-17).
Acyltransferases and transacylases
involved in fatty acid remodeling of phospholipids and metabolism of bioactive lipids in mammalian cells.
In addition, molecular studies of the genes encoding the lipid and FA biosynthetic enzymes, including the desaturases and transacylases
, is now more readily undertaken because of the availability of heterologous probes for these genes from various higher plant species.