CREB1

(redirected from transactivator protein)

CREB1

A gene on chromosome 2q34 that encodes a transcription factor of the leucine zipper family of DNA binding proteins, which binds as a homodimer to the cAMP-responsive element. CREB1 is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway.
References in periodicals archive ?
HBV encodes HBV transactivator protein, the X protein, which is implicated in pathogenesis of hepatocellular carcinoma.
Human immunodeficiency virus transactivator protein (Tat) stimulates chemotaxis, calcium mobilization, and activation of human polymorphonuclear leukocytes: implications for Tat-mediated pathogenesis.
transactivator protein overexpression [Tat]); alcohol's effects on alcohol cardiomyopathy (i.
Cells are stably transformed with an HBV genome under control of an operator/promoter target sequence which can activate expression of the HBV genome when bound by a cognate transactivator protein.
The specific target of the drug is a critical interaction between two virus components, the transactivator protein tat and the RNA structure TAR.
In nucleus many transactivator proteins like estrogen receptor-a (ERa) thyroid hormone receptor-AY1 (TRAY1) and signal transducer and activator of transcription-1a (STAT1a) are phosphorylated by translocated pMAPK.

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