tramadol


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analgesic

 [an″al-je´zik]
1. relieving pain.
2. pertaining to analgesia.
3. an agent that relieves pain without causing loss of consciousness.
narcotic analgesic opioid analgesic.
nonsteroidal antiinflammatory analgesic (NSAIA) nonsteroidal antiinflammatory drug.
opiate analgesic (opioid analgesic) any of a class of compounds that bind with a number of closely related specific receptors (opioid receptors) in the central nervous system to block the perception of pain or affect the emotional response to pain; such compounds include opium and its derivatives, as well as a number of synthetic compounds, and are used for moderate to severe pain. Chronic administration or abuse may lead to dependence.

tra·ma·dol

(trah'mă-dol),
An analgesic drug with a mechanism of action that is unusual in that one optic isomer exerts typical opioid-type effects and the other isomer interacts with the reuptake and/or release of norepinephrine and serotonin in nerve terminals.

tramadol

/tra·ma·dol/ (tram´ah-dol″) an opioid analgesic used as the hydrochloride salt for the treatment of pain following surgical procedures and oral surgery.

tramadol

(trăm′ə-dôl′)
n.
A synthetic analgesic, C16H25NO2, used in its hydrochloride form to treat moderate to moderately severe pain. It is structurally similar to codeine and has both opioid and nonopioid effects.

tramadol

a central analgesic.
indications It is used to manage moderate to severe pain.
contraindications Factors that prohibit its use are known hypersensitivity to this drug or acute intoxication with any central nervous system depressant.
adverse effects Seizures and GI bleeding are life-threatening effects. Other adverse effects are dizziness, central nervous system stimulation, somnolence, headache, anxiety, confusion, euphoria, hallucination, nausea, constipation, vomiting, dry mouth, diarrhea, abdominal pain, anorexia, flatulence, vasodilation, orthostatic hypotension, tachycardia, hypertension, abnormal electrocardiograms, pruritus, rash, urticaria, vesicles, urinary retention or frequency, menopausal symptoms, dysuria, and menstrual disorders.

tramadol

Ultram® Pharmacology An analgesic Adverse effects Constipation, N&V, vertigo, headache, somnolence, anaphylactoid reactions, drug abuse, seizures

tramadol

A centrally-acting synthetic opiate pain-killing drug. It is less likely to cause respiratory depression, constipation, euphoria and addiction than many of the ipioid agonists. It is currently the fourth most commonly prescribed analgesic in the world. Brand names are Tramake, Zamadol and Zydol.

tramadol

; Zamadol potent opioid analgesic; fewer side-effects than other opioids (i.e. less respiratory depression, constipation, addiction potential)

tramadol

an opioid partial μ agonist.
References in periodicals archive ?
Okeke, however, noted that because cocaine was not easily accessed, some people resort to using an overdose of Tramadol to get the desired 'high' effect.
She said: "We don't know for certain, but there is a strong probability that Daniel took too many Tramadol and accidentally overdosed.
Alhashemi and Kaki11 and Frikha et al12 not many researches have been carried out on intrathecal administration of tramadol.
sup][3] Tramadol poisoning is one of the most common causes of poisoning in Iran, and tramadol abuse and overdose have also increased in Iran recently.
He said tramadol is the most common drug found for that reason.
The Ajman Port and Customs has seized a large quantity of tramadol pills being smuggled through a ship coming from an African port.
The company said Tramadol Hydrochloride Extended-release Tablets USP, 100 mg, 200 mg and 300 mg is the generic version of Valeant's Ultram Extended-release Tablets.
The objective of this study was to compare the effect of tramadol as adjuvant to ropivacaine on the quality, duration of anaesthesia and postoperative analgesia in supraclavicular brachial plexus block.
Emergency department visits associated with the misuse or abuse of tramadol more than doubled from 2005 to 2011, while visits for adverse reactions to tramadol increased 1.