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toxicodynamics

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toxicodynamics
the physiological mechanisms by which toxins are absorbed, distributed, metabolized and excreted.


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The guidance is divided into four main sections covering each of the four different areas where CSAFs can be introduced: interspecies differences in toxicokinetics and toxicodynamics, and human variability in toxicokinetics and toxicodynamics.
Further information on the toxicodynamics of CMS (and colistin) is urgently required for its use in the treatment of infections caused by multidrug-resistant Gram negative bacteria.
 
 
 
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