An exercise in estimating the concentration of toxic alcohols and glycols is given, and the literature on poisoning with this unusual but commonly encountered intoxicant is briefly reviewed.
Propylene glycol, which is not normally considered in this differential, should be, because it causes the same biochemical abnormalities as the other toxic alcohols and glycols listed in the mnemonic.
The clinical presentation and laboratory findings of a patient with PG toxicity are essentially identical to those of patients poisoned with more toxic alcohols and glycols.
The finding of an anion gap metabolic acidosis with a concomitant osmolar gap is suggestive of intoxication with a toxic alcohol or glycol.
Jeffrey Brent of the University of Colorado Health Sciences Center in Denver along with the Methylpyrazole for Toxic Alcohols
Testing for acetaminophen, salicylates, iron, co-oximetry, iron, and toxic alcohols is discussed in Parts III and IV.
Recommendations for Specific Analysis of Ethyl Alcohol and Other Toxic Alcohols
Ethanol is also used as a therapeutic drug for patients with toxic alcohol intoxications and for ethanol withdrawal syndrome.
This experience suggests that even if the prevalence of toxic alcohol ingestion for a given geographic location is low, requests for these tests can be substantial because symptoms and signs consistent with toxic alcohol ingestion are frequently attributable to other clinical conditions.
A panel of experts will provide updates on new therapies for poisoning with lead, mercury, arsenic, toxic alcohols
, and cyanide will review the evolving drug-specific antibody therapies.
Toxic alcohol ingestions: clinical features, diagnosis, and management.
This case of a patient with ethylene glycol poisoning illustrates the difficulty of diagnosing the ingestion of this toxic alcohol.