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torsade de pointes

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tor·sade de pointes (tôr-säd d pwt)
n.
Paroxysms of ventricular tachycardia in which the electrocardiogram shows a steady undulation in the QRS axis in runs of 5 to 20 beats and with progressive changes in direction.

torsade de pointes
French, torsade–twist, Cardiology A form of polymorphic ventricular tachycardia with prolonged Q-T intervals initiated by a premature ventricular depolarization striking near the apex of a delayed T wave; torsades have irregular rates of 200-250/min with marked variability in amplitude and direction of a QRS wave that seems to twist around an isoelectric baseline; torsades may spontaneously resolve or evolve to ventricular tachyarrhythmia and may be nonspecific or due to drugs–eg, adrenergics, antihistamine, phenothiazine, procainamide, quinines, sotalol, and tricyclic antidepressants, electrolyte imbalance–eg, hypokalemia, hypomagnesemia, CNS hemorrhage or trauma, long Q-T wave syndrome, liquid diet, and underlying heart disease Management Isoproterenol


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Incidence of non-modifiable risk factors for Torsade de Pointes Overall, 22 (88%) patients were females and 19 (76%) patients had structural heart disease (Table 1).
class IA or class III antiarrhythmics) or in patients with risk factors for torsade de pointes (e.
 
 
 
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