tophus /to·phus/ (to´fus) pl. to´phi [L.] a deposit of sodium urate in the tissues about the joints in gout, producing a chronic, foreign-body inflammatory response.
Tophus (plural, tophi)
tophus
tophus
to·phus (t  f s)n. pl. to·phi (-f  ) 1. A deposit of urates in the skin and tissue around a joint or in the external ear. 2. Dental calculus; tartar. |
Tophus (plural, tophi)
A chalky deposit of a uric acid compound found in gout. Tophi occur most frequently around joints and in the external ear.
Mentioned in: Gout
tophus
[tō′fəs] pl. tophi
Etymology: L, tufa, porous rock
a calculus containing sodium urate that develops in fibrous tissue around joints, typically in patients with gout. -tophaceous, adj.
tophus
pl. tophi [L.]
1. a chalky deposit of sodium urate occurring in gout; tophi form most often around the joints in cartilage, bone, bursae and subcutaneous tissue.
2. dental calculus.
tophus
The pathognomonic lesion of gout, which appears grossly when preserved in alcohol or other non-aqueous solution as a nodular mass of white chalky, pasty material composed of crystalline and amorphous urates–eg, monosodium urate
monohydrates, surrounded by mononuclear cells, fibroblasts and a foreign body-type giant cell reaction with epithelioid histiocytes. See Gouty toe.
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