toll-like receptors


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toll-like receptors (TLR),

a family of pattern-recognition receptors in mammals that can discriminate between chemically diverse classes of microbial products, including bacterial cell-wall components; can elicit pathogen-specific innate cellular immune responses.
References in periodicals archive ?
Background: In vitro experiments have revealed that toll-like receptor 4 (TLR4) pathway is involved in the progression of immunoglobulin A nephropathy (IgAN) by induction of proinflammatory cytokines.
Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles.
Toll-like receptors (TLR) are present on the surface of platelets in smaller amounts than GPIb-IX-V complex.
TRIF mediates Toll-like receptor 5-induced signaling in intestinal epithelial cells.
Divergent Toll-like receptors in catfish (Ictalurus punctatus): TLR5S, TLR20, TLR21.
But since research shows increased inflammation in obese people, the Toll-like receptor and monocyte findings may help define individuals at high risk for obesity.
Toll-like receptors and innate immune responses in systemic lupus erythematosus.
Knowing the toll-like receptors are major determinants of the body's inflammatory response to viral and bacterial pathogens, we set out to see if these receptors were susceptible to insulin's effect.
So far, ten human Toll-related proteins are characterized, Toll-like receptors (TLRs) 1 to 10, with human called TLR4 (24), which is LPS's receptor.