Plasmacytoid CD123 (PCD) dendritic cells have tolerogenic
effects, and they gradually increase in number during the rejection-free post-transplant period.
Natural killer T cells recognize glycolipid antigens presented by CD1d molecule and may also play an important role in oral tolerance by inducing tolerogenic
dendritic cells and regulatory T cells, or by deleting antigen-specific T cells.
In addition, due to their direct cytotoxic properties, microtubule-depolymerizing agents like MMAE also appear to convert tumor-resident tolerogenic
dendritic cells into active antigen-presenting cells.
This determines whether there will be an inflammatory or tolerogenic
environment in the gut and other organs (Leclercq, 2016) (Galland, 2014).
Phenotype of IFN-gamma-Induced IDO+ Dendritic Cells Is Maintained via an Autocrine IDO-Kynurenine/AhR-IDO Loop.
As a result, KCs usually have tolerogenic
properties, meaning that they do not respond to all antigens with an immune response.
CD11c+, CD11b+ dendritic cells are abundant in Peyer's patches during the induction of oral tolerance to type II collagen and suppress experimental collagen-induced arthritis.
Costimulatory molecules on immunogenic versus tolerogenic
human dendritic cells.
The DCs full activation is controlled by Brucella and then this microbe uses the tolerogenic
properties of DCs to overthrow immune responses.
Regulatory mul titasking of tolerogenic
dendritic cellslessons taken from vitamin d3-treated tolerogenic
Kroemer, "Immunogenic and tolerogenic
cell death," Nature Reviews Immunology, vol.
Excretory-secretory products (ESP) from Fasciola hepatica induce tolerogenic
properties in myeloid dendritic cells.