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tolerogenic

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tol·er·o·gen·ic (tlr--jnk)
adj.
Producing immunological tolerance.


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While mature dendritic cells are responsible for activating the immune system, another type, called tolerogenic dendritic cells, are believed to suppress immune system activity.
In keeping with this, recent studies have identified tolerogenic T-cell peptides on Fel d 1 that are associated with the production of IL-10 in vitro and that stimulate increased IL-10 production in patients receiving allergen immunotherapy (Reefer et al.
McCurry, MD, director of the lung and heart-lung transplant unit of the University of Pittsburgh in Pennsylvania, presented results of a study that compared outcomes in 20 lung transplant patients treated with the tolerogenic protocol, developed by Thomas Starzl, MD, with 15 recipients who were not.
 
 
 
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