tolbutamide

tolbutamide /tol·bu·ta·mide/ (tol-bu´tah-mid) a sulfonylurea used as a hypoglycemic in the treatment of type 2 diabetes mellitus; the monosodium salt is used to test for insulinoma and diabetes mellitus.

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tol·bu·ta·mide (tl-byt-md)

n.

An orally active hypoglycemic agent used in the treatment of adult-onset diabetes mellitus.

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tolbutamide, (tolbū´tmīd´),

n brand name: Orinase;
drug class: sulfonylurea (first generation) oral antidiabetic;
action: causes functioning beta cells in pancreas to release insulin, leading to drop in blood glucose levels;
use: treatment of type II diabetes mellitus.

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tolbutamide

a first generation sulfonylurea derivative, used as an oral hypoglycemic agent in the treatment of diabetes mellitus.

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tolbutamide tolerance test

the blood sugar curve after an intravenous injection of the hypoglycemic agent tolbutamide parallels the curve in a glucose tolerance test.