titration


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titration

 [ti-tra´shun]
determination of a given component in solution by addition of a liquid reagent of known strength until a given endpoint, e.g., change in color, is reached indicating that the component has been consumed by reaction with the reagent.
Dean and Webb titration a test for measuring antibody in which varying dilutions of antibody are mixed with a constant quantity of antiserum; antibody activity is determined by the dilution in which flocculation occurs most rapidly, i.e., the end point.

ti·tra·tion

(tī-trā'shŭn),
Volumetric analysis by means of the addition of definite amounts of a test solution to a solution of the substance being assayed.
[Fr. titre, standard]

titration

/ti·tra·tion/ (ti-tra´shun) determination of a given component in solution by addition of a liquid reagent of known strength until the endpoint is reached when the component has been consumed by reaction with the reagent.

titration

[tītrā′shən]
a method of estimating the amount of solute in a solution. The solution is added in small, measured quantities to a known volume of a standard solution until a reaction occurs, as indicated by a change in color or pH or the liberation of a chemical product.

titration

Medtalk The serial dilution of a substance of interest. See Checkerboard titration.

ti·tra·tion

(tī-trā'shŭn)
Volumetric analysis by addition of definite amounts of a test solution to a solution of the substance being assayed.
[Fr. titre, standard]

ti·tra·tion

(tī-trā'shŭn)
Volumetric analysis by addition of definite amounts of a test solution to a solution of the substance being assayed.
[Fr. titre, standard]

titration (tītrā´shən),

n incremental increase in drug dosage to a level that provides the optimal therapeutic effect.

titration

1. in chemistry, the determination of a given component in solution by addition of a liquid reagent of known strength until a given end point, e.g. change in color, is reached indicating that the component has been consumed by reaction with the reagent.
2. in serology, the serial dilution of serum, often in two- or 10-fold steps to determine the highest dilution that still contains detectable amounts of antibody. The reciprocal of that dilution is referred to as the antibody titer of that serum.
3. in microbiology, the serial dilution of a suspension of microorganisms; each dilution, usually in replicas of 4 or 5, is then inoculated onto a substrate such as agar plate (bacteria) or cell culture (viruses) such that the number of organisms present in one or more of the higher dilutions can be accurately counted and used to infer the number of organisms in the original undiluted suspension.

Dean and Webb titration
a test for measuring antibody in which varying dilutions of antibody are mixed with a constant quantity of antigen; antibody activity is determined by the dilution in which flocculation occurs most rapidly, i.e. the end point.
References in periodicals archive ?
The primary outcome was the percentage of dose change alert confirmations and cancellations during the titration of high-alert medications, within the soft limits.
The child and parent are instructed to have the child actually fall asleep while wearing the mask for one or two nights prior to the CPAP titration study.
However, not all institutions have adopted this policy and continue to transfuse group O platelets to non-group O recipients without the benefit of antibody titration due to 1)a lack of a standardized method for performing isohemagglutinin titers, 2)reports of a widely varying range of titers implicated in such reactions, and 3) no formally adopted critical titer value above which these products should be transfused to non-group O patients.
2] titration Indicator cells (NZBS Reference Laboratory) and 25[micro]L of each master dilution were added to individual wells in a Diamed (now Biorad) Liss/ Coombs card.
Out of these, 36 were for a first time titration and 30 were referred for re-titration.
Content determination by titration is a widely used analytical technique, particularly for routine analysis of raw materials as well as final products.
A review of existing methods for the determination of sulfate ion yields several possibilities titration methods [10-12], but not IR-turbidimetric.
Students with very little laboratory practise can achieve very high levels of precision and accuracy in the titration volumes (error < 1%).
No studies are available in which a bolus of analgesic is used for procedural pain relief in ICU patients already treated with individualised titration of analgesia for pain at rest.
The amperometric titration is a sensitive and convenient analytical technique, based on the existence of a simple relationship between concentrations of an electro--active substance and a Polarographic current, Selenium and Tellurium have been determined in binary mixture in natural water and in alloys [7-8].
Fed up analysing with a tired, jaded and worn out titration system?
A compact instrument for Karl Fischer titration of difficult materials is now available from Metrohm.