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tissue factor pathway inhibitor

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tissue factor pathway inhibitor
(extrinsic factor) lipoprotein-associated coagulation inhibitor Hematology A coagulation factor X-dependent inhibitor of the factor VIIa/tissue factor complex; it is a plasma lipoprotein that regulates procoagulant effects of tissue factor; with Ca2+ and phospholipid, TFPI binds to and inhibits either free factor Xa or factors Xa and VIIa when associated with tissue factor-factor VIIa-Xa complex
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Tissue factor, tissue factor pathway inhibitor and cytoadhesive molecules in patients with an acute coronary syndrome.
G-CSF in acute myocardial infarction--experimental and clinical ... by Akar, Ahmet Ruchan; Durdu, Serkan; Topcuoglu, Pervin; Ince, Huseyin; Petzsch, Michael; Rehders, Tim / The Anatolian Journal of Cardiology (Anadolu Kardiyoloji Dergisi)
a clinical-stage pharmaceutical company developing therapeutics for treatment of anemia and cancer, announced that they have entered into a research collaboration for the synthesis and development of novel peptides that mimic certain fragments of tissue factor pathway inhibitor (TFPI).
EntreMed and Affymax form tissue factor pathway inhibitor peptides ... by BIOTECH Patent News
Inhibition of these activated coagulation pathways is maintained by (1) tissue factor pathway inhibitor, which prolongs the initiation stage of coagulation (low-level thrombin production); (2) AT, which decreases the rate of thrombin development during the propagation stage (explosive thrombin production)[3]; and (3) the protein C system, which is activated when thrombin binds with thrombomodulin on the vessel.
A review of disseminated intravascular coagulation: presentation, ... by Cunningham, Vickie L. / Medical Laboratory Observer
 
 
 
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