tissue dose


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tissue dose

the amount of radiation absorbed by tissue in the region of interest, expressed in rad.
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If the specific tissue dose is multiplied by the appropriate tissue weighting factor to obtain the equivalent whole-body dose, then dividing the equivalent whole-body dose by the tissue weighting factor should yield the specific tissue dose.
Specifically, the pharmacokinetic model can be used to predict the target tissue dose associated with an animal toxicity study conducted by one route, and then can be exercised to predict the equivalent human exposure by another route that would result in the same target tissue dose (22).
The modeling is used to quantify tissue doses and to describe the response of organisms to chemical exposures.