tirofiban

tirofiban /ti·ro·fi·ban/ (ti″ro-fi´ban) a platelet inhibitor, used as the hydrochloride salt in prophylaxis of thrombosis in unstable angina or in myocardial infarction that is not characterized by abnormal Q waves.

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tirofiban,

an antiplatelet agent.

indication It is used to treat acute coronary syndrome.

contraindications The following factors prohibit its use: known hypersensitivity to this drug, active internal bleeding, stroke, major surgery, severe trauma, intracranial neoplasm, aneurysm, and hemorrhage.

adverse effects Bleeding is a life-threatening effect of tirofiban. Other adverse reactions include bradycardia, dizziness, dissection, coronary artery edema, pain in the legs and/or pelvis, and sweating. Rash is a common side effect.

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tirofiban

Aggrastat^®, MK-383 Cardiology A potent short-acting, nonpeptide inhibitor of platelet glycoprotein IIb/IIIa or integrin α_IIbβ₃ receptor which, when administered with heparin, ↓ ischemic events in Pts with acute coronary syndrome. See PRISM, PRISM-PLUS.