thyroglobulin

thyroglobulin /thy·ro·glob·u·lin/ (thi″ro-glob´u-lin) an iodine-containing glycoprotein of high molecular weight, occurring in the colloid of the follicles of the thyroid gland; the iodinated tyrosine moieties of thyroglobulin form the active hormones thyroxine and triiodothyronine.

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thy·ro·glob·u·lin (thr-glby-ln)

n.

1. A thyroid protein that is the precursor to iodine-containing hormones and is typically present in the colloid of thyroid gland follicles.

2. A substance extracted from the thyroid glands of hogs, formerly used as a thyroid hormone supplement to treat hypothyroidism.

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thyroglobulin

1. an iodine-containing glycoprotein of high molecular weight, occurring in the colloid of the follicles of the thyroid gland; the iodinated tyrosine moieties of thyroglobulin form the active hormones thyroxine and tri-iodothyronine.

2. a substance obtained by fractionation of thyroid glands from the pig, administered orally as a thyroid supplement in the treatment of hypothyroidism.

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thyroglobulin

A 669 kD iodine-rich glycoprotein secreted by thyroid follicular cells into thyroid colloid where it is iodinated; once resorbed by follicular cells, it is cleaved into multiple units of T₃–iodothyronine and T₄–thyroxine. See T_{3, T4, Thyroid gland.}