thyrocalcitonin


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Related to thyrocalcitonin: thyroxine, triiodothyronine, parathyroid hormone

calcitonin

 [kal″sĭ-to´nin]
a polypeptide hormone secreted by the parafollicular or C cells of the thyroid gland; it is involved in plasma calcium homeostasis and acts to decrease the rate of bone resorption. Preparations of calcitonin are called either calcitonin-human or calcitonin-salmon; the former is a synthetic polypeptide with the same sequence as that occurring naturally in humans, and the latter is either derived from salmon or is a synthetic polypeptide of the same sequence as that found in salmon. They are used in the treatment of severe hypercalcemia, paget's disease of bone, and postmenopausal osteoporosis. Called also thyrocalcitonin.

cal·ci·to·nin

(kal'si-tō'nin),
A peptide hormone, of which eight forms in five species are known; composed of 32 amino acids and produced by the parathyroid, thyroid, and thymus glands; its action is opposite to that of parathyroid hormone in that calcitonin increases deposition of calcium and phosphate in bone and lowers the level of calcium in the blood; its level in the blood is increased by glucagon and by Ca2+ and thus opposes postprandial hypercalcemia.
Synonym(s): thyrocalcitonin
[calci- + G. tonos, stretching, + -in]

thyrocalcitonin

(thī′rō-kăl′sĭ-tō′nĭn)

thyrocalcitonin

calcitonin

; thyrocalcitonin hormone (secreted by parafollicular cells of thyroid) reducing plasma calcium (by increasing urinary calcium excretion and reducing osteoclastic bone resorption); used to treat Paget's disease

thyrocalcitonin

calcitonin.