BNO-1055 had no significant effect on the uptake of docetaxel or 5-fluorouracil (5-FU), a pyrimidine analog and inhibitor of thymidylate synthetase (TYMS), a key enzyme for de novo thymidine
The present paper comprises polarographic study of complexation of thymidine
with metal ions Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) ions in aqueous media at three temperatures.
Ganciclovir chemoablation of herpes thymidine
kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses.
phosphorylase gene mutations in MNGIE, a human mitochondrial disorder.
Measurement of thymidine
incorporation was first used to determine if the synergistic effects of mitomycin C and morphine on DNA damage are consistent with interference with repair processes by the opioid.
Reversibility of lipoatrophy in HIV-infected patients 2 years after switching from a thymidine
analogue to abacavir: the MITOX Extension Study.
In DNA the bases are paired, forming the famous double helix; cytidine always pairs with guanosine, and thymidine
always pairs with adenosine.
37) Multivariate analyses of data from the HIV Out-Patient Study (HOPS) cohort (23) indicate that the following are risk factors for lipoatrophy: exposure to and duration of thymidine
analogs (particularly stavudine and zidovudine), age, CD4 T-cell count, viral load, duration of therapy in general, and White race.
Intended as a research tool, the T790M quantitative mutation assay detects the presence of a mutant thymidine
base in a background of normal cytosine bases at position 2369 of the EGFR gene.
Biologic features and molecular characterization of hemagglutinin, thymidine
kinase, and vaccinia growth factor genes suggested a vaccinia virus infection, which strengthens the idea of the reemergence and circulation of vaccinia virus in Brazil.
The HSV-1-derived vectors are non-neurovirulent and do not spontaneously reactivate from latency, and they optionally contain a functional HSV thymidine
kinase gene, which can enhance the effectiveness against cancer of drug treatment with gancyclovir or acyclovir.
Following injection of [3H] thymidine
, draining lymph nodes were radioassayed on day 6.