THRIVE

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Thrombin Inhibitor in Venous Thromboembolism. A clinical study that assessed the efficacy of ximelagatran (Exanta), an oral thrombin inhibitor in preventing venous thrombo-embolism—VTE
Conclusions Ximelagatran is better than a placebo for extended prevention of VTE
Nonetheless, in 2004 the FDA rejected Exanta because of its adverse renal and cardiovascular effects
References in classic literature ?
So Little Jem was talked to and loved and cuddled; and he throve as became a child of the house of dreams.
Things came up there and grew and flowered exactly as my gardening books said they should do; and in front of me, in the gay orchard, things that nobody ever troubled about or cultivated or noticed throve joyously beneath the trees,--daffodils thrusting their spears through the grass, crocuses peeping out inquiringly, snowdrops uncovering their small cold faces when the first shivering spring days came.
An excellent man, who only wanted somebody to manage him; and, between ourselves, he found somebody to do it; and what is more, he throve on it and grew fat on it, and lived happy and died easy on it, dating from the day when my lady took him to church to be married, to the day when she relieved him of his last breath, and closed his eyes for ever.