thromboxane B2


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thromboxane B2 (TXB2)

a stable metabolite of thromboxane A2 that has an effect on polymorphonuclear cells and may possess chemotactic activity. It is released during anaphylaxis in laboratory animals. See also thromboxane A2.
References in periodicals archive ?
Biomarkers analysed from both urine and plasma samples included cortisol (also analysed from saliva), substance P (SUBP), leukotriene B4 (LTB4), thromboxane B2 (Tbx-B2) and midkine.
In addition, the levels of thromboxane B2 (TXB2) and prostaglandin E2 (PGE2) in collagen stimulated PRP were significantly inhibited in a concentration-dependent manner by indole-3-carbinol.
Their healing substances fight and directly block inflammatory compounds like prostaglandin E2, thromboxane B2, interleukin-6 and C-reactive protein.
She explains that the new assay measures levels of 11-dehydro thromboxane B2 which allows platelets to clump and which is secreted in the urine.
The AspirinWorks Test Kit is an enzyme-linked immunoassay (ELISA) to determine levels of 11dehydro thromboxane B2 (11dhTxB2) in human urine, which aids in the qualitative detection of aspirin effect in apparently healthy individuals post ingestion.
Naproxen significantly inhibited platelet aggregation and ex vivo thromboxane B2 synthesis and decreased urinary excretion of prostaglandin E2.
In fact, Simon et al (8) have shown in four phase II trials that celecoxib is effective in treating the signs and symptoms of osteoarthritis and rheumatoid arthritis, as well as showing that celecoxib is statistically significantly less likely than nonselective NSAIDs to cause gastric or duodenal erosions/ulcerations, (9) without any significant effect on platelet aggregation or thromboxane B2 levels.
FDA-cleared test that measures the urinary biomarker 11-dehydro thromboxane B2 (11dTxB2) to determine aspirin effect.
Platelet aggregation induced by low concentrations of adenosine diphosphate (ADP) and epinephrine, and serum thromboxane B2 decreased by 45% both in humans and animals after GLA supplementation.
TxA2 is rapidly hydrolyzed nonenzymatically to form thromboxane B2 (TxB2).
FDA-cleared test that measures the urinary biomarker 11-dehydro thromboxane B2 (11dhTxB2) to determine aspirin effect in apparently healthy individuals post ingestion.
The AspirinWorks Test determines the effect of aspirin on platelets by measuring the level of the biomarker called thromboxane B2 (11dhTxB2).