thrombotic microangiopathy


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microangiopathy

 [mi″kro-an″je-op´ah-the]
a disorder involving the small blood vessels. adj., adj microangiopath´ic.
thrombotic microangiopathy formation of thrombi in the arterioles and capillaries; proposed name for a syndrome that would include both thrombotic thrombocytopenic purpura and hemolytic uremic syndrome.

throm·bot·ic mi·cro·an·gi·op·a·thy

thrombosis within small blood vessels, as in thrombotic thrombocytopenic purpura.

thrombotic microangiopathy

the formation of thrombi in the arterioles and capillaries, as occurs in thrombotic thrombocytopenic purpura and hemolytic uremia syndrome.

microangiopathy

a disorder involving the small blood vessels.

cerebrospinal microangiopathy
in pigs is manifested by depression, incoordination, aimless wandering, circling and wasting. The characteristic microangiopathy is not restricted to the nervous system. Thought to be a sequel to chronic edema disease.
dietetic microangiopathy
one of the less commonly occurring lesions that can be prevented by the dietary addition of selenium and vitamin E.
thrombotic microangiopathy
formation of thrombi in the arterioles and capillaries.
References in periodicals archive ?
Diagnosis: pulmonary tumor thrombotic microangiopathy developing cor pulmonale.
VEGF inhibition and renal thrombotic microangiopathy.
aHUS is a chronic, ultra-rare, and life-threatening disease in which a genetic deficiency in one or more complement regulatory genes causes chronic uncontrolled complement activation, resulting in complement-mediated thrombotic microangiopathy (TMA), the formation of blood clots in small blood vessels throughout the body.
The clinical pictures were consistent with thrombotic microangiopathy and are the first reported cases of tiger snake envenomation associated thrombotic microangiopathy.
Thrombotic microangiopathy (TMA), which is histologically defined as the development of hyaline thrombi in small vessels, is a frequent finding in patients with thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS).
Thrombotic microangiopathy in malignant hypertension and hemolytic uremic syndrome (HUS)/thrombotic thrombocytopenic purpura (TTP): can we differentiate one from the other?
Consequently, the formation of thrombotic microangiopathy lesions occurs predominately in renal glomeruli and small renal arterioles.
Nonetheless, no data indicate that anticoagulation is beneficial for thrombotic microangiopathy, valvular heart disease, livedo reticularis, leg ulcers, or MRI abnormalities associated with cognitive dysfunction.
Detection of the proteolytic enzyme ADAMTS-13 may be used to differentiate between the forms of thrombotic microangiopathy (TMA), thrombotic thrombocytopenic purpura (TTP) and hemolytic-uremic syndrome (HUS).
Although the typical pathologic lesions of SLE and TTP both primarily involve arterioles, the characteristic histologic patterns are distinct: inflammation with vasculitis in SLE and platelet-rich thrombi without overt inflammation, termed thrombotic microangiopathy, in TTP.
coli infections: enteropathy, inflammation and vasculopathy, thrombotic microangiopathy, and nephropathy.
ABANO TERME, ITALY -- Much has been learned about triggering factors and the range of clinical manifestations in catastrophic antiphospholipid syndrome to describe a constellation of events including multiple organ failure, thrombotic microangiopathy, and tissue necrosis, but the pathogenesis is unclear and mortality remains in excess of 50%, said Dr.