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thrombospondin |
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thrombospondin /throm·bo·spon·din/ (throm?bo-spon´din) a glycoprotein that interacts with a wide variety of molecules, including heparin, fibrin, fibrinogen, platelet cell membrane receptors, collagen, and fibronectin, and plays a role in platelet aggregation, tumor metastasis, adhesion of Plasmodium falciparum, vascular smooth muscle growth, and tissue repair in skeletal muscle following crush injury. thrombospondin an osteoblast product which binds to connective tissues and serum proteins and binds calcium to hydroxyapatite and to osteonectin. |
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