These new coated prosthetic heart valves will be designed for hemodynamic performance and durability similar to uncoated materials, combined with a greater thromboresistance
, both in vitro and in animal studies.
Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD.
This technology, used in many of Gore's peripheral products, is intended to provide improved thromboresistance
within the branch component of the device.
The changes in functional moieties within structure of a solid organic polymer can influence its dielectric properties, degradability, hydrophilicity, permeation, adhesion, dye absorption, thromboresistance
, and cellular attachment, which are important factors for engineering and biomedical applications .
Dow Plastics announced a surface treatment technology that provides wettability, by reducing air bubble adhesion on plastic surfaces, and thromboresistance
, which inhibits blood clot formation.
These results indicate that the presence of hydrophilic PEO segments has much improved the thromboresistance
of segmented polyurethane and polyurethaneurea.
5 million grant from the National Institutes of Health (NIH) titled "Optimizing Cardiovascular Device Thromboresistance
for Eliminating Anticoagulants.
An improved heart valve with high thromboresistance
, MRI compatibility and reduced production cost is also being developed.
This heparin technology consists of a proprietary, covalent end-point attachment to the graft surface that is intended to provide sustained thromboresistance
, it said.
The GORE PROPATEN Vascular Graft has previously demonstrated improved thromboresistance
and patency compared to standard ePTFE grafts in pre-clinical in vivo tests.
Pyrolytic carbon is mainly used as an artificial heart valve material because of its good strength, wear resistance and durability, and most importantly, thromboresistance
or the ability to resist blood clotting.
Integrated radial support offers all the benefits of a ringed graft, while the GORE PROPATEN Bioactive Surface helps to improve thromboresistance